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Take Route 24 south to I-495 south or take Route 3 south to the Sagamore Bridge.
From Springfield / Worcester:
Take Mass Turnpike to I-495 south. Before Bourne Bridge take route 6 east along the Cape Cod Canal to the Sagamore Bridge.
From New York / Connecticut:
Take I-95 to Providence, RI, and then take I-195 east to Route 25 east and follow the Sagamore Bridge.
From Sagamore Bridge:
Cross the Sagamore Bridge and follow Route 6 to exit 9A. Merge right onto Route 134. Take a left on Route 28 (Main Street) and then take a right onto Depot Street. Follow Depot Street to Old Wharf Road and turn right onto Old Wharf Road. The Cutty Sark is ¼ mile on your right.